Sunday, February 21, 2010

I read about the side effects ; should I stop Medications?

Every thing you read on internet may not be written in the right perspective. Minoxidiil may be very rarely a possible cause of hepatic ( liver) damage but when it is consumed orally and not when you apply it on the scalp. Same way Finasteride side effect is mainly reduced sexual libido ( a psychological manifestation) and not really impotency or sterility ( organic manifestations) more over this is very well studied to be experienced by only 1% of those who use it and majority of the time that is experienced in initial few weeks. Most important and interesting is the sexual symptoms are reversible on stopping the medication and it has been seen that many of those who have continued in spite of the experience of initial sexual symptoms had observed that the said side effect disappeared. By not taking this you lose a chance of falling in to 99% of those who do not have such side effect and have benefit of medication. for more ref to:

http://goodbyehairloss.blogspot.com/2010/01/medications-used-for-hair-loss.html

http://goodbyehairloss.blogspot.com/2010/01/hair-loss-medication-minoxidil.html

http://goodbyehairloss.blogspot.com/2010/01/hair-loss-and-medications-finasteride.html If you have been using this medications for long time and you already had benefit if improving your the thickness and length of your miniaturized hairs you may start rapidly losing those hairs which are supported by the medications if you suddenly stop the medications. Minoxidil is better used as 5% instead of 2% for more efficiency and use twice instead of oncee a day. In my experience Instead of plain Minoxidil as you have been using; use the combination with Reti-A which is more effective and have to be used once a day. check: http://goodbyehairloss.blogspot.com/2010/01/minoxidil-with-retin-or-minoxidil.html Finasteride is better than Minoxidil in effect when used alone but since both medications have different mechanism of action there is more benefit when used in combination.

Saturday, February 13, 2010

Transplant of Hair from others or animal : is it possible?



Each follicular unit of hair has blood vessels, glands, nerves, skin, and fat. It takes all this plus a growth center and the right genes and nutrition to make hair grow. Since by definition hair is an organ, transplanting the hair from someone else is like transplanting a heart, kidney, lung, etc.
One may tend to think that a person (a Family, friend or well wisher) with same blood group if willing to donate hair to another person should be an easy solution for people with hair loss but it is not that easy a solution!
Generally hair transplantation from one person to another (called Allogenic or Homologous Transplant) who could be living person or a dead person (Cadaveric Transplant) carries the similar risks as organ (liver, heart, kidney) transplants.
Transplant from the animal fur to human head is called Heterogenous or Xeno Transplant. There is a
1. Risk of rejection and failure
2. Wastes money and effort of surgery
3. Lifelong use of anti-rejection medication that could lead to further health complications
4. Transmission of some diseases.
5.It involves surgery on the donor as well
6. There are medico legal aspects to it besides ethical issues: such as possibility of people selling their hair for money in future.
Such experiment has been done before without success (http://www.hairsite.com/hair-loss-articles/article308-person-to-person-hair-transplant.htm)
Hair from a newborn baby or identical twins (they have same Genetic Blue print) might be immune privileged (it seems to work for a heart transplant), but again, who would endorse such a donor? Incidence of transplant from one identical twin to another has worked in the past but the problem is that when one twin has balding, so does the other.
There are some research indicating that Anagen Bulb part of Human hair follicle is Immune Privileged (i.e. protected from Host Rejection)
http://www.nature.com/jidsp/journal/v8/n2/full/5640115a.html ). More research may open a new vista in this field in future.
Rosati et al. reported the case that the bone marrow transplant patients could undergo an allotransplant of hair from the same bone marrow donor. Jahoda et al. (http://www.nature.com/nature/journal/v402/n6757/full/402033a0.html)