Mesotherapy (from Greek mesos, "middle", and therapy from Greek therapeia, "to treat medically") is a non-surgical cosmetic medicine treatment. Mesotherapy employs multiple injections of pharmaceutical and homeopathic medications, plant extracts, vitamins, and other ingredients into the subcutaneous fat. Dr. Michel Pistor (1924-2003) performed clinical research and founded the field of mesotherapy. There is no conclusive research proof that these chemical compounds work to target adipose (fat cells) specifically. Some physicians[have expressed concern over the efficacy of mesotherapy, arguing that the treatment hasn't been studied enough to make a determination. It is expressed by Rod Rohrich, M.D., Chairman, Dept. of Plastic Surgery, University of Texas Southwestern Medical Center, Dallas: "There is simply no data, no science and no information, to my knowledge, that mesotherapy works,"
For experiences of Mesotherapy one can refer to this link as well: http://www.realself.com/Mesotherapy/reviews
Besides ineffectiveness the possible allergy and long term side effects of
the drugs are never studied well.
More over it is advised to be taken and continued at few weeks interval for maintenance
Usually by a thin needle of 30 number gauge either manually or by a mesotherapy computerized mesogun aided injection (or as some people use dermaroller which makes tiny tunnel to channel the drug in the skin) of liquid containing vitamins, minerals and hormones or in case of hair loss treatment Finasteride or Minoxidil area injected in subdermal layer in a very small quantity at say every 1 cm distance of the bald area of scalp Skin. It is said that Vit. B 6 or pyridoxine, Azailic acid and Zinc are found to be 5 alfa reductase enzyme inhibitors (and in turn DHT inhibitors) in some research and some people inject these molecules as well.
There is although always a concern of Hypotension ( drop in blood pressure) if Minoxidil is directly injected as it is the Hypotensive medication when given systematically. Finsteride has not been found to be effective locally any ways.
These appear to be just claims rather than good science in this treatment, so one should be cautioned about this. In case od Dermaroller the needles penetrate the stratum corneum, the hard outer surface of the epidermal layer of the scalp.It is claimed that hundreds of tiny channels are created through the stratum corneum, which facilitate the passage and absorption of Minoxidil into the dermis to maximize it’s absorption by the hair follicles.
The Derma Roller also stimulates blood flow to the hair follicles via direct scalp massage. The dermal damage induces the release of growth factors that stimulate the production of new collagen and elastin and stimulates the miniaturized hairs to grow stronger.
